Catalytic Trends of OsO4 for the Taurine-Bromamine-T Redox System: Kinetic and Mechanistic Chemistry of Catalyzed and Uncatalyzed Reactions

Abstract

Taurine (2-ethane aminosulfonic acid) facilitates as a building block for protein synthesis, also possessing various other vital biological functions. Literature survey revealed that there was no report available on the oxidation of taurine with any oxidants from its kinetic, mechanistic and catalytic aspects. A detailed comparative mechanistic study of its Os(VIII) catalyzed and uncatalyzed oxidation kinetics by bromamine-T (BAT) in NaOH medium at 313 K revealed the rate law to be: -d[BAT]/dt=k [OH^-]^0.63[Os(VIII)]¹ for former and -d[BAT]/dt=k[OH^-]^0.77 for latter. The influence of dielectric constant of the medium on the rate of reaction was studied. The rate of reaction remained invariant on the addition of NaBr, NaClO₄ and p-toluenesulfonamide (PTS) to the reaction mixture. The oxidation product taurine was characterized as sulfoacetic acid. An enhanced four-fold reaction rate was observed for the Os(VIII) catalyzed reaction relative to the uncatalyzed reaction. With the aid of temperature studies on the rate of reaction, the activation parameters were assessed. Based on experimental results, elegant reaction schemes and relevant rate laws have been worked out.

Cite this Article

Ramya Radhakrishnan Puttaswamy. Catalytic Trends of OsO4 for the Taurine-Bromamine-T Redox System: Kinetic and Mechanistic Chemistry of Catalyzed and Uncatalyzed Reactions. Journal of Catalyst & Catalysis. 2017; 4(3): 5–19p.