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Review of Hydroxyapatite Coating: Enhances Bioactivity and Osteoconductivity in Natural Hard Tissues

Purva Saxena

Abstract


Hydroxyapatite (HA or HAP) of biologically (produced from coral, cattle, or marine algae) or synthetic origin is used to repair and regenerate bone in the form of granules, blocks, and scaffolds, either alone or in a composite with polymers or other ceramics, or as a coating on dental or orthopedics implants. From the perspective of enhancing bioactivity, numerous methods for surface alteration and its combinations have been suggested. The composite (HAp), an osteoconductive material, is one surface treatment technique covered in this paper's overview. Pyro processing and hydro processing are the two different categories of coating techniques. Utilizing hydro processing, HAp, carbonate apatite (CO3-Ap), a CO3-Ap/CaCO3 composite, HAp/collagen, and a HAp/gelatin composite are all used to coat titanium substrates. Evaluation using surface-modified samples implanted in rat tibiae is presented. The potential of hydroxyapatite (HA) coating to promote early bone regeneration to cementless prosthesis components served as the primary driving force behind their clinical use. The objective is to enhance the lengthy survival of knee replacements by increasing implant fixation and reducing particle migrating into the bone-to-implant interface.


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References


Yamamoto D, Kawai I, Kuroda K, Ichino R, Okido M, Seki A. Osteoconductivity of anodized titanium with controlled micron-level surface roughness. Materials Transactions. 2011;52(8):1650–1654

Kuroda K, Moriyama M, Ichino R, Okido M, Seki A. Formation and osteoconductivity of hydroxyapatite/collagen composite films using a thermal substrate method in aqueous solutions. Materials Transactions. 2009;50(5):1190–1195.

Chang MC, Ko CC, Douglas WH. Preparation of hydroxyapatite-gelatin nanocomposite. Biomaterials. 2003;24(17):2853–2862.

Chang MC, Ikoma T, Kikuchi M, Tanaka J. Preparation of a porous

hydroxyapatite/collagen nanocomposite using glutaraldehyde as a crosslinkage agent. Journal of Materials Science Letters. 2001;20(13):1199–1201.

Zhang Q, Chen J, Feng J, Cao Y, Deng C, Zhang X. Dissolution and mineralization behaviors of HA coatings. Biomaterials. 2003;24(26):4741–4748.

Kuroda K, Moriyama M, Ichino R, Okido M, Seki A. Formation and in Vivo evaluation of carbonate apatite and carbonate apatite/CaCO 3 composite films using the thermal substrate method in aqueous solution. Materials Transactions. 2008;49(6):1434–1440.

Tang R, Henneman ZJ, Nancollas GH. Constant composition kinetics study of carbonated apatite dissolution. Journal of Crystal Growth. 2003;249(3-4):614–624.

Kuroda K, Nakamoto S, Miyashita Y, Ichino R, Okido M. Osteoinductivity of hydroxyapatite films with different surface morphologies coated by the thermal substrate method in aqueous solutions. Journal of the Japan Institute of Metals. 2007;71(3):342–345.

Ziani-Cherif H, Abe Y, Imachi K, Matsuda T. Hydroxyapatite coating on titanium by thermal substrate method in aqueous solution. Journal of Biomedical Materials Research. 2002;59(2):390–397

Nie X, Leyland A, Matthews A. Deposition of layered bioceramic

hydroxyapatite/TiO 2 coatings on titanium alloys using a hybrid technique of micro- arc oxidation and electrophoresis. Surface and Coatings Technology. 2000;125(1–3):407–414.


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