Synthesis, Characterization and Drug Delivery Application of Poly (Acid Fuchsin) Based Triblock Copolymer

Abstract

Synthesis, characterization and its drug delivery application of Poly (acid fuchsin) (PAF) was done under inert atmosphere. The (M₀/I₀) was maintained at 100. In order to increase the molecular weight and processability, it was block copolymerized with ε-caprolactone (CL) and tetrahydrofuran (THF) separately. The conductivity value of PAF was found to be decreased after the chemical conjugation with poly(ε-caprolctone) (PCL) and poly(tetrahydrofuran) (PTHF) blocks. Thus obtained triblock copolymer was subjected to humidity sensor application and the results were critically compared. The triblocks were further characterized by Fourier transform infrared (FTIR) spectroscopy, UV-visible spectroscopy, fluorescence spectroscopy, differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), gel permeation chromatography (GPC), field emission scanning electron microscopy (FESEM) and cyclic voltammetry (CV).

Keywords: Synthesis, ring opening polymerization, differential scanning calorimetry, humidity sensor study, drug release system