An Efficient Synthesis of Annulated Novel Dihydropyridine Derivatives using Zeolite H-BEA and Zeolite BEA-SO3H

Authors

  • Kalpana C. Maheria Applied Chemistry Department, S. V. National Institute of Technology, Ichchhanath, Surat-395007, Gujarat, India
  • Manoj Kumar K. Rathod Applied Chemistry Department, S. V. National Institute of Technology, Ichchhanath, Surat-395007, Gujarat, India
  • Sunil R. Mistry Applied Chemistry Department, S. V. National Institute of Technology, Ichchhanath, Surat-395007, Gujarat, India
  • Suban K. Sahoo Applied Chemistry Department, S. V. National Institute of Technology, Ichchhanath, Surat-395007, Gujarat, India

DOI:

https://doi.org/10.37591/jocc.v1i2.2331

Keywords:

Zeolite BEA-SO3H, Hantzsch reaction, MCRs, quinoline and benzoquinoline substituted dihydropyridines

Abstract

Modified zeolite (zeolite BEA-SO3H) was synthesized with intent to improve the surface area and Si/Al ratio by loading chlorosulphonic acid onto zeolite H-BEA. Parent and modified zeolite were characterized by variety of characterization techniques such as, ICP, FT-IR, XRD, TGA, NH3-TPD,BET surface area, etc. The catalytic applications of parent and modified zeolite H-BEA were demonstrated through the synthesis of novel quinoline and benzoquinoline substituted dihydropyridines (DHPs) via one pot Hantzsch cyclocondensation reaction. This method affords high percentage yield of DHPs (93%) within short reaction times. The effects of catalysts and substituent’s (different quinolines and benzoquinoline carbaldehydes) on the synthesis of DHPs were studied and related reaction mechanism was proposed

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Published

2019-04-16

Issue

Vol. 1 No. 2 (2014)

Section

Articles

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