Open Access Open Access  Restricted Access Subscription or Fee Access

Recording on Passive Capillary Flow of Dyed Working Liquids in the Polymer based Microfluidic Devices Fabricated inside the Cleanroom Laboratory

Subhadeep Mukhopadhyay

Abstract


In this experimental work, author has fabricated total 13 individual microfluidic devices using the maskless lithography, hot embossing lithography, direct bonding technique, diamond like carbon (DLC) coating, and laboratory-made clamping inside the cleanroom laboratory using author’s own hands-on completely. Polymethylmethacrylate (PMMA) is the chosen polymer to fabricate the 10 individual microfluidic devices due to its plasticity and optical transparency. Dyed water, dyed ethylene glycol and dyed ethanol are the prepared working liquids in this work to record the passive capillary flows in the fabricated devices. A CMOS camera catching 25 frames per second with a corresponding resolution of 0.04 second is used to record each passive capillary flow. After recording, each passive capillary flow is observed to be leakage-free due to the proper sealing by direct bonding technique. Also, total 3 individual passive capillary flows of dyed working liquids are demonstrated corresponding to three individual SU-8 based glass microfluidic devices. This work may be useful in commercial bioengineering applications by control on working liquids inside the microfluidic lab-on-a-chip systems.  


Keywords


Thin film; Coating science; Gradual expansion; Sudden expansion; Microchannel bend; Capillary flow

Full Text:

PDF

References


] S. Mukhopadhyay, J. P. Banerjee, S. S. Roy, S. K. Metya, M. Tweedie, J. A. McLaughlin, “Effects of Surface Properties on Fluid Engineering Generated by the Surface-Driven Capillary Flow of Water in Microfluidic Lab-on-a-Chip Systems for Bioengineering Applications”, Surface Review and Letters, Vol. 24 (2017) Page 1750041.

S. Mukhopadhyay, J. P. Banerjee, A. Mathur, M. Tweedie, J. A. McLaughlin, S. S. Roy, “Experimental Studies of Surface-Driven Capillary Flow in PMMA Microfluidic Devices Prepared by Direct Bonding Technique and Passive Separation of Microparticles in Microfluidic Laboratory-on-a-Chip Systems”, Surface Review and Letters, Vol. 22 (2015) Page 1550050.

S. Mukhopadhyay, “Experimental Investigations on the Interactions between Liquids and Structures to Passively Control the Surface-Driven Capillary Flow in Microfluidic Lab-on-a-Chip Systems to Separate the Microparticles for Bioengineering Applications”, Surface Review and Letters, Vol. 24 (2017) Page 1750075.

S. Mukhopadhyay, “Experimental Investigations on the Surface-Driven Capillary Flow of Aqueous Microparticle Suspensions in the Microfluidic Laboratory-on-a-Chip Systems”, Surface Review and Letters, Vol. 24 (2017) Page 1750107.

S. Mukhopadhyay, “Experimental Investigations on the Effects of Surface Modifications to Control the Surface-Driven Capillary Flow of Aqueous Working Liquids in the PMMA Microfluidic Devices”, Advanced Science, Engineering and Medicine, Vol. 9 (2017) Pages 959-970.

S. Mukhopadhyay, “Novel Recording of the Surface-Driven Capillary Flow of Water in a PMMA Microfluidic Device by CMOS Camera”, Research & Reviews: Journal of Physics, Vol. 6, Issue 1 (2017) Pages 16-21.

D. Mattia, Y. Gogotsi, “Review: Static and Dynamic Behavior of Liquids inside Carbon Nanotubes”, Microfluid Nanofluid, Vol. 5 (2008) Pages 289-305.

W. Sparreboom, A. V. D. Berg, J. C. T. Eijkel, “Transport in Nanofluidic Systems: A Review of Theory and Applications”, New Journal of Physics, Vol. 12 (2010) Page 015004.

D. Mijatovic, J. C. T. Eijkel, A. V. D. Berg, “Technologies for Nanofluidic Systems: Top-Down vs. Bottom-Up -------- A Review”, Lab Chip, Vol. 5 (2005) Pages 492-500.

M. Rauscher, S. Dietrich, “Wetting Phenomena in Nanofluidics”, Annu. Rev. Mater. Res., Vol. 38 (2008) Pages 143-172.

T. M. Squires, S. R. Quake, “Microfluidics: Fluid Physics at the Nanoliter Scale”, Reviews of Modern Physics, Vol. 77 (2005) Pages 977-1026.

H. A. Stone, A. D. Stroock, A. Ajdari, “Engineering Flows in Small Devices: Microfluidics Toward a Lab-on-a-Chip”, Annu. Rev. Fluid Mech., Vol. 36 (2004) Pages 381-411.

D. Erickson, D. Li, “Integrated Microfluidic Devices”, Analytica Chimica Acta, Vol. 507 (2004) Pages 11-26.

A. Bange, H. B. Halsall, W. R. Heineman, “Microfluidic Immunosensor Systems”, Biosensors and Bioelectronics, Vol. 20 (2005) Pages 2488-2503.

P. Abgrall, A. M. Gue, “Lab-on-Chip Technologies: Making a Microfluidic Network and Coupling it into a Complete Microsystem----A Review”, J. Micromech. Microeng., Vol. 17 (2007) Pages R15-R49.

S. Mukhopadhyay, “Aspects of Diamond-Like Carbon based MEMS and Micro-Fluidic Devices”, Journal of Petroleum Engineering and Technology, Vol. 8, Issue 1 (2018) Pages 31-33.

S. Mukhopadhyay, “Passive Capillary Flow of Aqueous Working Liquids in the Straight PMMA Microchannels of Rectangular Cross-Sections”, Journal of Petroleum Engineering and Technology, Vol. 8, Issue 2 (2018) Pages 5-8.

S. Mukhopadhyay, “Passive Capillary Flow of Aqueous Working Liquids in the SU-8 based Micro-Channel Bends”, Emerging Trends in Chemical Engineering, Vol. 5, Issue 1 (2018) Pages 20-22.

S. Mukhopadhyay, “Passive Capillary Flow of Red Dye in the SU-8 based Glass Microfluidic Devices”, Trends in Mechanical Engineering and Technology, Vol. 7, Issue 3 (2018) Pages 59-61.

S. Mukhopadhyay, “Passive Capillary Flow of Dyed Aqueous Ethanol in the Leakage-Free PMMA Microchannel”, International Journal of Renewable Energy and its Commercialization, Vol. 4, Issue 1 (2018) Pages 12-14.

S. Mukhopadhyay, “Passive Capillary Flow of Dyed Aqueous Isopropyl Alcohol in the Leakage-Free SU-8 based Glass Microfluidic Devices”, International Journal of Chemical Engineering and Processing, Vol. 4, Issue 1 (2018) Pages 30-32.

S. Mukhopadhyay, J. P. Banerjee, S. S. Roy, “Effects of Channel Aspect Ratio, Surface Wettability and Liquid Viscosity on Capillary Flow Through PMMA Sudden Expansion Microchannels”, Advanced Science Focus, Vol. 1 (2013) Pages 139-144.

S. Mukhopadhyay, J. P. Banerjee, S. S. Roy, “Effects of Liquid Viscosity, Surface Wettability and Channel Geometry on Capillary Flow in SU8 based Microfluidic Devices”, International Journal of Adhesion and Adhesives, Vol. 42 (2013) Pages 30-35.

S. Mukhopadhyay, “Optical Recording of Flow Phenomena in Photoresist based Microfluidic Devices”, Trends in Opto-Electro and Optical Communication, Vol. 10, Issue 1 (2020) Pages 36-42.

S. Mukhopadhyay, “Thermodynamic Explanation on Surface-Driven Capillary Flow of Working Liquids in the Microfluidic Devices Fabricated by Polymers”, International Journal of Thermodynamics and Chemical Kinetics, Vol. 6, Issue 1 (2020) Pages 45-70.

S. Mukhopadhyay, “Surface-Driven Capillary Flow of Dyed Ethanol in a Single SU-8 based Microchannel Bend Fabricated on Glass”, International Journal of Thermodynamics and Chemical Kinetics, Vol. 6, Issue 1 (2020) Pages 29-34.




DOI: https://doi.org/10.37591/jotcsta.v7i3.4538

Refbacks

  • There are currently no refbacks.