Review of Hydroxyapatite Coating: Enhances Bioactivity and Osteoconductivity in Natural Hard Tissues

Authors

  • Purva Saxena Student, Department of Biotechnology, Invertis Village, Delhi Lucknow Highway NH-24, Bareilly, Uttar Pradesh

Abstract

Hydroxyapatite (HA or HAP) of biologically (produced from coral, cattle, or marine algae) or synthetic origin is used to repair and regenerate bone in the form of granules, blocks, and scaffolds, either alone or in a composite with polymers or other ceramics, or as a coating on dental or orthopedics implants. From the perspective of enhancing bioactivity, numerous methods for surface alteration and its combinations have been suggested. The composite (HAp), an osteoconductive material, is one surface treatment technique covered in this paper's overview. Pyro processing and hydro processing are the two different categories of coating techniques. Utilizing hydro processing, HAp, carbonate apatite (CO3-Ap), a CO3-Ap/CaCO3 composite, HAp/collagen, and a HAp/gelatin composite are all used to coat titanium substrates. Evaluation using surface-modified samples implanted in rat tibiae is presented. The potential of hydroxyapatite (HA) coating to promote early bone regeneration to cementless prosthesis components served as the primary driving force behind their clinical use. The objective is to enhance the lengthy survival of knee replacements by increasing implant fixation and reducing particle migrating into the bone-to-implant interface.

References

Yamamoto D, Kawai I, Kuroda K, Ichino R, Okido M, Seki A. Osteoconductivity of anodized titanium with controlled micron-level surface roughness. Materials Transactions. 2011;52(8):1650–1654

Kuroda K, Moriyama M, Ichino R, Okido M, Seki A. Formation and osteoconductivity of hydroxyapatite/collagen composite films using a thermal substrate method in aqueous solutions. Materials Transactions. 2009;50(5):1190–1195.

Chang MC, Ko CC, Douglas WH. Preparation of hydroxyapatite-gelatin nanocomposite. Biomaterials. 2003;24(17):2853–2862.

Chang MC, Ikoma T, Kikuchi M, Tanaka J. Preparation of a porous

hydroxyapatite/collagen nanocomposite using glutaraldehyde as a crosslinkage agent. Journal of Materials Science Letters. 2001;20(13):1199–1201.

Zhang Q, Chen J, Feng J, Cao Y, Deng C, Zhang X. Dissolution and mineralization behaviors of HA coatings. Biomaterials. 2003;24(26):4741–4748.

Kuroda K, Moriyama M, Ichino R, Okido M, Seki A. Formation and in Vivo evaluation of carbonate apatite and carbonate apatite/CaCO 3 composite films using the thermal substrate method in aqueous solution. Materials Transactions. 2008;49(6):1434–1440.

Tang R, Henneman ZJ, Nancollas GH. Constant composition kinetics study of carbonated apatite dissolution. Journal of Crystal Growth. 2003;249(3-4):614–624.

Kuroda K, Nakamoto S, Miyashita Y, Ichino R, Okido M. Osteoinductivity of hydroxyapatite films with different surface morphologies coated by the thermal substrate method in aqueous solutions. Journal of the Japan Institute of Metals. 2007;71(3):342–345.

Ziani-Cherif H, Abe Y, Imachi K, Matsuda T. Hydroxyapatite coating on titanium by thermal substrate method in aqueous solution. Journal of Biomedical Materials Research. 2002;59(2):390–397

Nie X, Leyland A, Matthews A. Deposition of layered bioceramic

hydroxyapatite/TiO 2 coatings on titanium alloys using a hybrid technique of micro- arc oxidation and electrophoresis. Surface and Coatings Technology. 2000;125(1–3):407–414.

Downloads

Published

2022-09-14

Issue

Vol. 9 No. 2 (2022)

Section

Review Articles

License

Declaration and Copyright Transfer Form

(to be completed by authors)

I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.

  • I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
  • I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
  • I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
  •  I/We also agree to the authorship of the article in the following order:

Author’s name                                    

 

1. ________________

2. ________________

3. ________________

4. ________________

 

We  Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal.