Short Report on Polymer Based Automated Fluid Machines for Applications in Microfluidics

Authors

  • Subhadeep Mukhopadhyay Assistant Professor, Department of Electronics and Communication Engineering, National Institute of Technology Arunachal Pradesh, Yupia, District-Papum Pare, Arunachal Pradesh, India

Keywords:

PMMA, Maskless lithography, Hot embossing, Ethylene glycol, Water

Abstract

In this experimental work, a couple of gradual expansion microchannels are fabricated by polymethylmethacrylate (PMMA) using the maskless lithography, hot embossing lithography and direct bonding technique. Dyed ethylene glycol and dyed water are the prepared working liquids. The CMOS camera catching 25 frames per second with a corresponding time-scale resolution of 0.04 second is used to record each surface-driven microfluidic flow of dyed ethylene glycol and dyed water in the fabricated devices. Leakage-free microfluidic flow is recorded in each case due to proper direct bonding technique. The surface-driven microfluidic flow is governed due to thermodynamic effect. 100% separation efficiency is experimentally achieved in the polymer-based microfluidic lab-on-a-chip systems as automated fluid machines after filtration of polystyrene microparticles from aqueous microparticle suspensions. This particular experimental work may be suitable for commercial microfluidic applications.

References

C. C. Chang, R. J. Yang. Electrokinetic Mixing in Microfluidic Systems. Microfluid Nanofluid. 2007; 3: 501-525.

F. Mugele, J. C. Baret. Electrowetting: from Basics to Applications. Journal of Physics: Condensed Matter. 2005; 17: 705-774.

R. Pethig. Review Article-Dielectrophoresis: Status of the Theory, Technology, and Applications. Biomicrofluidics. 2010; 4: 022811.

S. Mukhopadhyay, J. P. Banerjee, S. S. Roy, et.al. Effects of Surface Properties on Fluid Engineering Generated by the Surface-Driven Capillary Flow of Water in Microfluidic Lab-on-a-Chip Systems for Bioengineering Applications. Surface Review and Letters. 2017; 24(3): 1750041.

S. Mukhopadhyay, S. S. Roy, Raechelle A. D'Sa, et.al. Nanoscale Surface Modifications to Control Capillary Flow Characteristics in PMMA Microfluidic Devices. Nanoscale Research Letters. 2011; 6: 411.

S. Mukhopadhyay, J. P. Banerjee, S. S. Roy. Effects of Channel Aspect Ratio, Surface Wettability and Liquid Viscosity on Capillary Flow through PMMA Sudden Expansion Microchannels. Advanced Science Focus. 2013; 1(2): 139-144.

R. S. Khurmi, J. K. Gupta. Theory of Machines. India: S. Chand and Company Limited; 2018.

D. Pnueli, C. Gutfinger. Fluid Mechanics. U.K.: Cambridge University Press. 2014.

B. Majumdar. Fluid Mechanics with Laboratory Manual. India: PHI Learning Private Limited. 2011.

K. Subramanya. Fluid Mechanics and Hydraulic Machines. Second edition. India: McGraw Hill Education (India) Private Limited. 2019.

F. M. White. Fluid Mechanics. 8th edition. India: McGraw Hill Education (India) Private Limited. 2017.

F. M. White. Viscous Fluid Flow. 3rd edition. India; Tata McGraw Hill Education Private Limited. 2012.

P. N. Modi, S. M. Seth. Hydraulics and Fluid Mechanics including Hydraulics Machines. 21st edition. India: Standard Book House; 2017.

S. K. Mitra, S. Chakraborty. Microfluidics and Nanofluidics Handbook: Fabrication, Implementation, and Applications. USA: CRC Press, Taylor and Francis Group; 2012.

P. R. Waghmare, S. K. Mitra. Finite Reservoir Effect on Capillary Flow of Microbead Suspension in Rectangular Microchannels. Journal of Colloid and Interface Science. 2010; 351: 561-569.

A. A. Saha, S. K. Mitra. Effect of Dynamic Contact Angle in a Volume of Fluid (VOF) Model for a Microfluidic Capillary Flow. Journal of Colloid and Interface Science. 2009; 339: 461-480.

A. A. Saha, S. K. Mitra, M. Tweedie, et.al. Experimental and Numerical Investigation of Capillary Flow in SU8 and PDMS Microchannels with Integrated Pillars. Microfluid Nanofluid. 2009; 7: 451-465.

M Raffel, C Willert, S Wereley, et.al. Particle Image Velocimetry: A Practical Guide. Second Edition. Germany: Springer. 2007.

Published

2021-10-01

Issue

Section

Articles