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Application of Graphene in Health and Medical Areas

Rabindranath Jana, Sahil Shaw, Souroshik Routh

Abstract


A comprehensive overview of the current state of graphene research in the health and biomedical field are presented here. The graphene and its derivatives hold immense potential for various applications in biotechnology, biomedicine, and bioengineering. The unique physicochemical properties of graphene, such as thermal conductivity and high-specific area, make it a promising material for advancements in drug delivery, bio-imaging, biosensors, and tissue engineering. However, there is an increasing anxiety surrounding the safety and biocompatibility of graphene. As the research on graphene grows, understanding the potential risks associated with its use in living organisms becomes crucial. Balancing the promising applications with thorough investigations into potential toxicological impacts is essential for responsible development in the field. We focus on discussing graphene synthetic strategies, functionalization, processibility protocols, and in vitro/in vivo applications provides a well rounded exploration of the material's journey from production to practical implementation. Addressing limitations and toxicological impacts is a responsible approach, ensuring that the transition of graphene materials into clinical tools is guided by a thorough understanding of potential risks and challenges. The need for new trends and guidelines for future developments demonstrates an awareness of the dynamic nature of scientific research and the importance of adapting to emerging knowledge. Continuous evaluation and refinement of guidelines are essential as the field progresses.

Keywords


Graphene, Biomedical Application, Medical science, Drug Delivery, Graphene Medical devices.

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References


A. K. Geim & K. S. Novoselov, The rise of graphene. Nature Materials, 2007, 183–191.

Daniel R. Dreyer, Rodney S. Ruoff, Christopher W. Bielawski, From Conception to Realization:

An Historial Account of Graphene and Some Perspectives for Its Future, Angewandte Chemie, 2010, 49, 9336–9344.

Giacomo Reina, José Miguel González-Domínguez, Alejandro Criado, Ester Vázquez, Alberto Bianco and Maurizio Prato. Promises, facts and challenges for graphene in biomedical applications. Chemical Society Reviews, 2017, 4400–4416.

K. S. Novoselov, A. K. Geim, S. V. Morozov, D. Jiang, Y. Zhang, S. V. Dubonos, I. V. Grigorieva,

and A. A. Firsov, Electric Field Effect in Atomically Thin Carbon Films, Science, 2004, 306, 666–669.

Magda Silva, Isabel S. Pinho, José A. Covas, Natália M. Alves & Maria C. Paiva, 3D printing of

graphene-based polymeric nanocomposites for biomedical applications, Functional Composite Materials, 2021, 265,

S. Syama, P. M. Safety and biocompatibility of graphene: A new generation nanomaterial for

biomedical application. International Journal of Biological Macromolecules, 2016, 86, 546–55.

Laraba, Selsabil Rokia, Luo, Wei, Rezzoug, Amine, Zahra, Qurat ul ain, Zhang, Shihao, Wu,

Bozhen, Chen, Wen, Xiao, Lan, Yang, Yuhao, Wei, Jie, & Li, Yulin, Graphene-based composites

for biomedical applications. Green Chemistry Letters and Reviews, 2022, 122, 724–748.

Thabitha P. Dasari Shareena, Danielle McShan, Asok K. Dasmahapatra & Paul B. Tchounwou, A

Review on Graphene-Based Nanomaterials in Biomedical Applications and Risks in Environment

and Health, Nanomicro Lett.2018, 10, 53

Yanwu Zhu, Shanthi Murali, Weiwei Cai, Xuesong Li, Ji Won Suk, Jeffrey R. Potts, Rodney S.

Ruoff, Graphene and Graphene Oxide: Synthesis, Properties, and Applications. Advanced

Materials, 2010, 5226–5226.

Yuxi Xu, Hua Bai, Gewu Lu, Chun Li, and Gaoquan Shi, Flexible Graphene Films via the Filtration

of Water-Soluble Noncovalent Functionalized Graphene Sheets. J. Am. Chem. Soc. 2008, 130(18),

–5857.




DOI: https://doi.org/10.37591/jotcsta.v10i3.7888

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